Head: Priv.Doz. Dr.med.univ. Tobias Zrzavy, PhD
Our research group investigates pathological mechanisms in inflammatory diseases of the central nervous system. The focus of our work is on Multiple Sclerosis (MS), the most common neurological disease in young adults. Additionally, we study other neuroinflammatory diseases such as antibody-mediated autoimmune encephalitis, neuromyelitis optica spectrum disorders, and MOG antibody-associated disease.
In our research laboratory, we characterize immune cells from blood and cerebrospinal fluid of patients with neuroinflammatory diseases using high-resolution and state-of-the-art molecular biological techniques. Our focus is on decoding fundamental mechanisms of autoimmunity and analyzing immunological changes under various disease-modifying therapies. In complementary studies, we examine the expression of disease-relevant proteins in archived MS brains to characterize the phenotypic properties and migration pathways of immune cells as well as the underlying inflammatory cascades. The systematic analysis of diagnostically obtained cerebrospinal fluid serves as a 'Window to the Brain,' providing us with unique insights into the local pathological processes of the central nervous system.
Contact us for more information on our research or on individual projects:
Priv.Doz.Dr.med.univ. Tobias Zrzavy, PhD
E-Mail: tobias.zrzavy@meduniwien.ac.at
Tel.: +43 (0)1 40400-31170